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The standard dose escalation protocol Based on the Phase 2 clinical trial data published in the New England Journal of Medicine, the typical retatrutide dose schedule follows a pattern like this: During the starting phase, a single 10mg vial reconstituted with 2mL of bacteriostatic water can last up to 10 weeks at a 1mg weekly dose

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In large, well designed, 24-week trials, combination therapy with saxagliptin 5 mg once daily plus metformin significantly improved HbA 1c levels relative to single-agent saxagliptin or metformin in treatment-naive patients

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